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天麻醒脑胶囊对家兔小板聚集和花生四烯酸诱导大鼠脑血栓形成的影响

       CAIYONGBIZHUOFANGFACEDINGTIANMAXINGNAOJIAONANGZAITINEIHETIWAIDUIXIANGANERLINSUAN(ADP)、HUASHENGSIXISUAN(arachidonic acid,AA) HEXUEXIAOBANHUOHUAYINZI(platelet activating factor,PAF)YOUDAOJIATUXUEXIAOBANHUOHUAJUJIDEYINGXIANG。CAIYONGCONGJINGDASHUJING NEIDONGMAIZHUSHEYOUFATONGCEDANAOBANQIUNAOXUESHUANXINGCHENGFANGFAPINGJIATIANMAXINGNAOJIAONANGDEKANGNAOXUESHUANXINGCHENGZUOYONG。TIANMAXINGNAOJIAONANGZAITIWAI CHENGNONGDUYILAIXINGMINGXIANYIZHICONGHEADPYINQIDEXUEXIAOBANJUJI,QIBANSHUYIZHINONGDU(50%of inhibitory concentration,IC50) FENBIEWEI1.83HE3.25g/L。0.5HE1g/kgDETIANMAXINGNAOJIAONANGYUGUANWEIHOUMINGXIANYIZHICONGYOUDAODEJIATUXUEXIAOBANJUJI,BENPIN 1g/kgSHIXIANZHUZUYIADPYINQIDEXUEXIAOBANJUJI。TIANMAXINGNAOJIAONANGZAITINEIWAIDUIPAFYOUDAODEXUEXIAOBANJUJIJUNWUMINGXIANYINGXIANG。 1、2g/kgTIANMAXINGNAOJIAONANGZUDEYOUCEYUZUOCENAOZHONGCHAZHIJUNXIANZHUJIANXIAO,XIANZHUJIANGDIYOUNAOYIWENSILANXIGUANGDUYUYOUNAOZHONGDEBIZHI。 JIEGUOTISHI,TIANMAXINGNAOJIAONANGJUYOUJIAOQIANGDEKANGXUEXIAOBANHEJIANQINGNAOXUESHUANXINGCHENGZUOYONG,YOULIYUXUEXIAOBANJUJIXINGZENGGAODEXUESHUANSHUANSAIXING JIBINGDEFANGZHI。

 

 

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